Accepted Preprint first posted online on 5 December 2008
Journal of Molecular Endocrinology 2009;42:185.
Journal of Molecular Endocrinology (2008) In press DOI: 10.1677/JME-08-0150
© 2008 Society for Endocrinology
How to study lipodomes
Tuulikki Seppanen-Laakso and
Matej Oresic
T Seppanen-Laakso, VTT Technical Research Centre, Espoo, Finland
M Oresic, VTT Technical Research Centre, Espoo, Finland
Correspondence: Matej Oresic, Email: matej.oresic{at}vtt.fi
Abstract
Lipidome is loosely defined as the entire spectrum of lipids in a biological system. Given the modern lipidomics platforms for the first time empower us with the ability to obtain a snapshot of complete cellular/organismal lipidome, many surprises and discoveries are likely awaiting us in the area lipids as related to cellular/organismal physiology. The lipidomics approaches can be applied both as the phenotyping platform as well as for hypothesis driven research aiming to elucidate, e.g., a specific pathway or gene function. Modern lipidomics methods combine the latest mass spectrometry technology and bioinformatics methods with traditional methods such as for sample preparation and lipid extraction.
Copyright © 2008 by the Society for Endocrinology.