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Accepted Preprint first posted online on 5 December 2008

Journal of Molecular Endocrinology 2009;42:185.

Journal of Molecular Endocrinology (2008) In press  DOI: 10.1677/JME-08-0150
© 2008 Society for Endocrinology

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Review

How to study lipodomes

Tuulikki Seppanen-Laakso and Matej Oresic

T Seppanen-Laakso, VTT Technical Research Centre, Espoo, Finland
M Oresic, VTT Technical Research Centre, Espoo, Finland

Correspondence: Matej Oresic, Email: matej.oresic{at}vtt.fi

Abstract

Lipidome is loosely defined as the entire spectrum of lipids in a biological system. Given the modern lipidomics platforms for the first time empower us with the ability to obtain a snapshot of complete cellular/organismal lipidome, many surprises and discoveries are likely awaiting us in the area lipids as related to cellular/organismal physiology. The lipidomics approaches can be applied both as the phenotyping platform as well as for hypothesis driven research aiming to elucidate, e.g., a specific pathway or gene function. Modern lipidomics methods combine the latest mass spectrometry technology and bioinformatics methods with traditional methods such as for sample preparation and lipid extraction.







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Copyright © 2008 by the Society for Endocrinology.